Male infertility counts for almost 30% of the total cases of infertility. Male infertility can be caused by several and various factors such as environmental, genetic and hormonal factors. Male infertility can be diagnosed through semen sample analysis; a fresh semen sample can indicate different semen abnormalities. A semen sample can indicate Azoospermia, Cryptozoospermia (Co) or Severe Oligozoospermia (ESO), which can cause infertility in male. It is challenging for an andrologist to distinguish between ESO and CO in clinic diagnose since both show no sperm in the sample in the initial sample test. In Cryptozoospermia or Severe Oligozoospermia, cryopreservation plays a significant part in preserving male fertility by freezing the individual sperm.